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Anaphylaxis


Signs and Symptoms of Anaphylaxis

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(Last Updated On: March 14, 2015)

Anaphylaxis can be defined as severe, life-threatening, systemic or generalized hypersensitivity (allergic) reaction. Generally speaking most common causes for severe allergic reaction (anaphylaxis) include food, drugs and venom. It must be identified and reacted to immediately in the emergency as time is very crucial in these cases, which can be a deciding factor between life and death. Here is a short overview of pharmacologic treatment of anaphylaxis. There are three drugs that are mainly used in any case of anaphylaxis. These include adrenaline, hydrocortisone and chlorphenamine. Doses of these drugs in case of anaphylaxis for different age groups are given below.

1. Adrenaline:

In case of anaphylaxis adrenaline is to be given intramuscularly and most appropriate site for intramuscular injection is anterolateral aspect of middle third of thigh.

Dose for less than 6 month age group

150 micrograms.

Dose for 6 months to 6 years age group

150 micrograms.

Dose for 6 to 12 years age group

300 microgram.

Dose for adults and children more than 12 years of age

500 micrograms

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Anaphylaxis

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