8 Types and Causes of Polyneuropathy


(Last Updated On: April 25, 2017)

5. Painful Polyneropathy:

Neuropathic Pain
Painful Polyneuropathy Can Be Very Disabling

Predominant symptom of this type of polyneuropathy is neuropathic pain, which is severe and usually burning in nature. Following are the causes of this kind of pain.

I. Guillain-Barre Syndrome (GBS)

II. Vasculitis

III. Amyloidosis

IV. Carcinomatous Infiltration

V. HIV

VI. Leprosy

VII. Diabetes Mellitus

VIII. Uraemia

6. Demyelinating Polyneuropathy

Bilogical Cascade Leading to Demyelination in CIDP
Mechanism of Demyelination in Chronic Inflammatory Demyelinating Polyneuropathy

Underlying pathology of this kind of neuropathy is demyelination, which is usually patchy and can occur at any site along the course of the nerve. Following are the causes of this kind of polyneuropathy.

I. Guillain-Barre Syndrome (GBS)

II. Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

III. Multifocal Motor Neuropathy (MMN)

IV. Hereditary Motor & Sensory Neuropathy Type I (HMSN I)

IV. Paraproteinaemic

V. HIV

VI. Drugs such as Amiodarone

7. Small Fiber Axonal Polyneuropathy:

Difference Between Small Fiber Polyneuropathy and Other Types of Polyneuropathies
Comparison of Small Fiber Polyneuropathy With Other Types of Polyneuropathies

This type of polyneuropathy affects axons only and that too only small ones. Following conditions lead to this kind of plyneuropathy.

I. Guillain-Barre Syndrome (GBS)

II. Leprosy

III. HIV

IV. Amyloid

V. Hereditary Sensory and Autonomic Neuropathy (HSAN)

VI. Fabry’s Disease

VII. Tangier Disease

8. Large Fiber Axonal Polyneuropathy:

Large Fiber Axonal Polyneuropathy Causes Distal Sensory and Motor Symptoms
Distal Wasting in Large Fiber Axonal Polyneuropathy

This type of polyneuropathy affects axons and that too only large ones. following conditions can result in large fiber axonal polyneuropathy:

I. Vasculitis

II. Paraneoplastic

III. Toxic

IV. Diabetes Mellitus

V. Porphyria

VI. Uremia

VII. Vitamin B12 Deficiency

VIII. Hereditary Motor & Sensory Neuropathy Type 2 (HMSN 2)

IX. Friedreich’s Ataxia

9. Autonomic Neuropathy:

Autonomic neuropathy affects autonomic fibers and is caused by following conditions:

1. Guillain-Barre Syndrome

2. Chronic Inflammatory Demyelinating Polyneuropathy

3. HIV

4. Paraneoplastic

5. Porphyria

6. Diabetes Mellitus

VII. Toxins

VIII. Hereditary Sensory & Autonomic Neuropathy

IX. Amyloidosis

 

 

 

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8 Types and Causes of Polyneuropathy